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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

beta-thalassemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

myeloid leukemia

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

hematologic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

large b-cell lymphoma diffuse

,

diffuse intrinsic pontine glioma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

,

lymphoid leukemia

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

interdigitating dendritic cell sarcoma

,

,

phenylketonurias

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

hodgkin disease

,

,

myeloid leukemia acute

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

bronchiolitis obliterans syndrome

,

non-hodgkin lymphoma

,

,

multiple myeloma

,

hodgkin disease

,

plasma cell neoplasms

,

lymphoid leukemia

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

large-cell lymphoma anaplastic

,

b-cell chronic lymphocytic leukemia

,

reactive arthritis

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

,

chronic obstructive pulmonary disease

,

,

,

obstructive lung diseases

,

psoriatic arthritis

,

allergic rhinitis

,

,

respiratory tract diseases

,

,

bronchial diseases

,

,

,

kasabach-merritt syndrome

,

hemangioendothelioma

,

,

,

cognitive dysfunction

,

,

,

chronic urticaria

,

,

breast neoplasms

,

,

,

alopecia areata

,

,

,

invasive candidiasis

,

renal insufficiency

,

carotid artery diseases

,

atherosclerosis

,

neoplasm metastasis

,

endocrine system diseases

,

,

pituitary dwarfism

,

juvenile arthritis

,

chronic disease

,

failure to thrive

,

psychotic disorders

,

,

mental disorders

,

,

tobacco use disorder

,

anxiety disorders

,

,

pulmonary emphysema

,

ulcerative colitis

,

,

,

,

,

,

rheumatoid arthritis

,

spontaneous remission

,

myelodysplastic syndromes

,

pharmacokinetics

,

thoracic neoplasms

,

invasive hydatidiform mole

,

parkinson disease

,

nerve degeneration

,

pancreatic neoplasms

,

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

,

castration-resistant prostatic neoplasms

,

,

brain neoplasms

,

,

colonic neoplasms

,

non-hodgkin lymphoma

,

follicular lymphoma

,

neuroendocrine tumors

,

kidney neoplasms

,

hypersensitivity

,

epstein-barr virus infections

,

myeloid leukemia acute

,

mouth neoplasms

,

oropharyngeal neoplasms

,

,

,

microsatellite instability

,

pancreatic ductal carcinoma

,

adenocarcinoma of lung

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

urethral neoplasms

,

ureteral neoplasms

,

,

local neoplasm recurrence

,

rectal neoplasms

,

laryngeal neoplasms

,

hypopharyngeal neoplasms

,

,

,

x-linked bulbo-spinal atrophy

,

,

,

malignant fibrous histiocytoma

,

nasopharyngeal carcinoma

,

,

,

unknown primary neoplasms

,

,

hematologic diseases

,

b-cell chronic lymphocytic leukemia

,

bone marrow diseases

,

endometrioid carcinoma

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

colonic diseases

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

pelvic neoplasms

,

environmental biomarkers

,

inflammatory breast neoplasms

,

intestinal neoplasms

,

kidney diseases

,

,

,

nervous system diseases

,

neoplasms by histologic type

,

nerve tissue neoplasms

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

salivary gland neoplasms

,

thyroid neoplasms

,

,

carcinoid tumor

,

vulvar neoplasms

,

parotid neoplasms

,

reactive arthritis

,

gastrointestinal stromal tumors

,

,

central nervous system neoplasms

,

spinal cord neoplasms

,

adenoviridae infections

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

uterine neoplasms

,

,

mullerian mixed tumor

,

basal cell carcinoma

,

basal cell neoplasms

,

,

male breast neoplasms

,

uveal neoplasms

,

,

,

,

colorectal neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

breast neoplasms

,

neoplasm metastasis

,

squamous cell carcinoma

,

head and neck neoplasms

,

ovarian neoplasms

,

stomach neoplasms

,

liver neoplasms

,

urinary bladder neoplasms

,

hepatocellular carcinoma

,

,

endometrial neoplasms

,

prostatic neoplasms

,

small cell lung carcinoma

,

esophageal neoplasms

,

hodgkin disease

,

,

uterine cervical neoplasms

,

squamous cell neoplasms

,

transitional cell carcinoma

,

ovarian epithelial carcinoma

,

multiple myeloma

,

urologic neoplasms

,

esophageal squamous cell carcinoma

,

biliary tract neoplasms

,

fallopian tube neoplasms

,

cholangiocarcinoma

,

nasopharyngeal neoplasms

,

plasma cell neoplasms

,

bile duct neoplasms

,

merkel cell carcinoma

,

,

gallbladder neoplasms

,

malignant mesothelioma

,

cutaneous malignant melanoma

,

peritoneal neoplasms

,

hematologic neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

,

,

,

b-cell lymphoma marginal zone

,

t-cell lymphoma cutaneous

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

,

,

diffuse intrinsic pontine glioma

,

multiple myeloma

,

,

brain neoplasms

,

,

plasma cell neoplasms

,

,

healthy volunteers/patients

,

type 1 diabetes mellitus

,

insulin resistance

,

,

,

,

squamous cell carcinoma of head and neck

,

multiple myeloma

,

head and neck neoplasms

,

,

t-cell lymphoma peripheral

,

,

protein c deficiency

,

plasma cell neoplasms

,

neoplasm metastasis

,

rheumatoid arthritis

,

sleep initiation and maintenance disorders

,

intrinsic sleep disorders

,

granulosa cell tumor

,

wounds and injuries

,

traumatic brain injuries

,

craniocerebral trauma

,

,

colonic neoplasms

,

subarachnoid hemorrhage

,

colorectal neoplasms

,

chronic renal insufficiency

,

chronic kidney failure

,

,

,

,

von willebrand diseases

,

non-small-cell lung carcinoma

,

diabetes mellitus

,

primary immunodeficiency diseases

,

essential hypertension

,

,

,

,

,

ulcerative colitis

,

type 2 diabetes mellitus

,

thrombotic thrombocytopenic purpura

,

cardiovascular diseases

,

,

viral pneumonia

,

glucose metabolism disorders

,

,

prostatic neoplasms

,

,

,

ischemic stroke

,

large b-cell lymphoma diffuse

,

interdigitating dendritic cell sarcoma

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

hodgkin disease

,

,

large-cell lymphoma anaplastic

,

,

precocious puberty

,

non-hodgkin lymphoma

,

,

alpha 1-antitrypsin deficiency

,

t-cell lymphoma

,

hematologic diseases

,

chronic obstructive pulmonary disease

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

mucopolysaccharidosis ii

,

Globulin, immune

hematologic neoplasms

,

,

transitional cell carcinoma

,

pancreatic ductal carcinoma

,

neurofibromatosis 1

,

hereditary sensory and autonomic neuropathies

,

multiple sclerosis

,

thyroid neoplasms

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

t-cell lymphoma cutaneous

,

,

merkel cell carcinoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

retinal detachment

,

wet macular degeneration

,

polypoidal choroidal vasculopathy

,

atopic dermatitis

,

pancreatic neoplasms

,

esophageal squamous cell carcinoma

,

adenocarcinoma of lung

,

,

,

liver neoplasms

,

head and neck neoplasms

,

hepatocellular carcinoma

,

ovarian neoplasms

,

urologic neoplasms

,

hodgkin disease

,

burkitt lymphoma

,

triple negative breast neoplasms

,

prostatic neoplasms

,

,

,

,

,

vascular diseases

,

myeloid leukemia

,

urologic diseases

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

mycosis fungoides

,

esophageal neoplasms

,

macular degeneration

,

ovarian epithelial carcinoma

,

brain neoplasms

,

endometrial neoplasms

,

invasive hydatidiform mole

,

,

diabetes mellitus

,

diabetic retinopathy

,

disease progression

,

male breast neoplasms

,

dermatomyositis

,

hypercholesterolemia

,

interstitial cystitis

,

,

,

postherpetic neuralgia

,

immune system diseases

,

blood protein disorders

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

hemostatic disorders

,

paraproteinemias

,

immunoproliferative disorders

,

hemorrhagic disorders

,

waldenstrom macroglobulinemia

,

kidney diseases

,

glandular and epithelial neoplasms

,

,

urinary bladder diseases

,

monocytic leukemia acute

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

hematopoietic stem cell transplantation

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

,

chronic hepatitis b

,

persistent infection

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

neurofibromatoses

,

,

cytokine release syndrome

,

systemic scleroderma

,

,

diffuse scleroderma

,

meningeal neoplasms

,

colorectal neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

myeloid leukemia acute

,

renal cell carcinoma

,

,

squamous cell carcinoma of head and neck

,

plasma cell neoplasms

,

alzheimer disease

,

,

,

colonic neoplasms

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

urinary bladder neoplasms

,

b-cell lymphoma

,

knee osteoarthritis

,

,

rectal neoplasms

,

kidney neoplasms

,

squamous cell carcinoma

,

follicular lymphoma

,

neoplasm metastasis

,

juvenile arthritis

,

,

rectal diseases

,

squamous cell neoplasms

,

meningococcal infections

,

non-muscle invasive bladder neoplasms

,

aplastic anemia

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

urogenital neoplasms

,

hip osteoarthritis

,

,

hematologic diseases

,

cardiovascular diseases

,

neoplasms by site

,

stomach neoplasms

,

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

adenosquamous carcinoma

,

large cell carcinoma

,

,

,

antibody formation

,

neoadjuvant therapy

,

kidney transplantation

,

residual neoplasm

,

small cell carcinoma

,

rheumatoid arthritis

,

,

multiple myeloma

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

healthy volunteers/patients

,

ankylosing spondylitis

,

psoriatic arthritis

,

,

ulcerative colitis

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

tick-borne encephalitis

,

,

pharmacokinetics

,

,

spondylarthritis

,

axial spondyloarthritis

,

pneumococcal infections

,

,

non-radiographic axial spondyloarthritis

,

electrocardiography

,

,

rheumatic fever

,

papulosquamous skin diseases

,

inflammatory bowel diseases

,

spondylarthropathies

,

rheumatic diseases

,

,

meningococcal meningitis

,

,

vaccine immunogenicity

,

,

medical sociology

,

castration-resistant prostatic neoplasms

,

,

neoplasm metastasis

,

bone marrow diseases

,

non-small-cell lung carcinoma

,

,

squamous cell neoplasms

,

,

prostatic neoplasms

,

,

transitional cell carcinoma

,

,

hypersensitivity

,

,

kidney diseases

,

renal insufficiency

,

bites and stings

,

squamous cell neoplasms

,

adenosquamous carcinoma

,

thoracic neoplasms

,

,

,

,

squamous cell carcinoma of head and neck

,

invasive hydatidiform mole

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

triple negative breast neoplasms

,

esophageal neoplasms

,

,

,

,

,

ductal carcinoma

,

testicular neoplasms

,

stomach neoplasms

,

,

biliary tract neoplasms

,

pancreatic neoplasms

,

head and neck neoplasms

,

male breast neoplasms

,

urologic neoplasms

,

deglutition disorders

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

ovarian neoplasms

,

inflammatory breast neoplasms

,

fallopian tube neoplasms

,

ductal carcinoma breast

,

prostatic neoplasms

,

mucinous adenocarcinoma

,

peritoneal neoplasms

,

brain stem neoplasms

,

castration-resistant prostatic neoplasms

,

non-hodgkin lymphoma

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