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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

breast neoplasms

,

,

non-hodgkin lymphoma

,

,

,

prostatic neoplasms

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

precursor cell lymphoblastic leukemia-lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

hematologic neoplasms

,

,

diffuse intrinsic pontine glioma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

myelomonocytic leukemia juvenile

,

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

myelomonocytic leukemia acute

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

bronchiolitis obliterans syndrome

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

,

phenylketonurias

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

myelodysplastic syndromes

,

,

hodgkin disease

,

myeloid leukemia

,

myeloid leukemia acute

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

,

healthy volunteers/patients

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

extranodal nk-t-cell lymphoma

,

adult t-cell leukemia-lymphoma

,

t-cell leukemia

,

,

sezary syndrome

,

mycosis fungoides

,

,

hepatic insufficiency

,

prolymphocytic leukemia t-cell

,

prolymphocytic leukemia

,

multiple myeloma

,

hodgkin disease

,

,

hematologic neoplasms

,

,

reactive arthritis

,

,

enteropathy-associated t-cell lymphoma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

large granular lymphocytic leukemia

,

,

immunoblastic lymphadenopathy

,

rheumatoid arthritis

,

,

coronavirus infections

,

,

,

,

head and neck neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

non-hodgkin lymphoma

,

t-cell lymphoma

,

follicular lymphoma

,

t-cell lymphoma peripheral

,

b-cell lymphoma marginal zone

,

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

,

,

brain neoplasms

,

,

diffuse intrinsic pontine glioma

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

renal cell carcinoma

,

human influenza

,

nutritional status

,

pneumococcal infections

,

pneumococcal pneumonia

,

,

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

inflammatory bowel diseases

,

,

,

tendon injuries

,

,

haemophilus influenzae

,

streptococcus pneumoniae

,

,

,

,

energy metabolism

,

endometrial neoplasms

,

,

mullerian mixed tumor

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

,

falciparum malaria

,

ovarian neoplasms

,

brain neoplasms

,

healthy volunteers/patients

,

prostatic neoplasms

,

,

,

colorectal neoplasms

,

squamous cell carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

ovarian epithelial carcinoma

,

cutaneous malignant melanoma

,

,

type 1 diabetes mellitus

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

sickle cell anemia

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

chronic hepatitis b

,

,

primary myelofibrosis

,

hepatocellular carcinoma

,

liver neoplasms

,

fallopian tube neoplasms

,

pancreatic neoplasms

,

,

hematologic neoplasms

,

ductal carcinoma

,

circulating neoplastic cells

,

uterine neoplasms

,

uterine cervical neoplasms

,

,

streptococcus agalactiae

,

,

follicular lymphoma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

invasive hydatidiform mole

,

biliary tract neoplasms

,

uveal neoplasms

,

respiratory tract diseases

,

respiration disorders

,

,

focal segmental glomerulosclerosis

,

cytomegalovirus infections

,

chronic hepatitis

,

kidney diseases

,

membranous glomerulonephritis

,

nephrotic syndrome

,

,

,

endometrioid carcinoma

,

breast diseases

,

squamous cell neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

,

pulmonary tuberculosis

,

adenocarcinoma of lung

,

disease progression

,

peritoneal neoplasms

,

,

beta-thalassemia

,

,

sickle cell trait

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

head and neck neoplasms

,

inflammatory breast neoplasms

,

,

respiratory syncytial virus infections

,

,

bacterial infections

,

,

streptococcal infections

,

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

infectious skin diseases

,

bacterial skin diseases

,

ductal carcinoma breast

,

renal insufficiency

,

,

,

,

urinary bladder neoplasms

,

acute coronary syndrome

,

,

rotavirus infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

respiratory syncytial viruses

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

acquired immunodeficiency syndrome

,

,

chronic obstructive pulmonary disease

,

communicable diseases

,

,

obstructive lung diseases

,

,

dental focal infection

,

focal infection

,

,

,

immunologic deficiency syndromes

,

ventilator-associated pneumonia

,

growth and development

,

immunologic tests

,

,

alzheimer disease

,

wasting syndrome

,

,

,

insulin resistance

,

abdominal obesity

,

lipid metabolism

,

latent autoimmune diabetes in adults

,

community-acquired infections

,

,

,

staphylococcal infections

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

thyroid neoplasms

,

papillary thyroid cancer

,

thyroid diseases

,

clostridioides difficile

healthy volunteers/patients

,

castration-resistant prostatic neoplasms

,

,

stomach neoplasms

,

,

hepatic insufficiency

,

neoplasm metastasis

,

,

colorectal neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

,

pheochromocytoma

,

,

,

non-hodgkin lymphoma

,

multiple myeloma

,

endometrial neoplasms

,

alveolar soft part sarcoma

,

,

adenoid cystic carcinoma

,

carcinoid tumor

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

malignant mesothelioma

,

,

hemangiosarcoma

,

,

,

breast neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

neoadjuvant therapy

,

renal cell carcinoma

,

,

,

kidney neoplasms

,

non-small-cell lung carcinoma

,

pancreatic neoplasms

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

,

ovarian neoplasms

,

,

gastrointestinal stromal tumors

,

mantle-cell lymphoma

colonic neoplasms

,

non-hodgkin lymphoma

,

pharmacokinetics

,

hematologic neoplasms

,

b-cell chronic lymphocytic leukemia

,

neoplasm micrometastasis

,

neuroendocrine tumors

,

medical sociology

,

thrombocytopenia

,

connective and soft tissue neoplasms

,

paraneoplastic syndromes

,

,

renal insufficiency

,

vaginal neoplasms

,

vulvar neoplasms

,

rectal neoplasms

,

,

,

,

colorectal neoplasms

,

,

kidney neoplasms

,

liver neoplasms

,

,

biliary tract neoplasms

,

,

,

hepatocellular carcinoma

,

thyroid neoplasms

,

,

,

gallbladder neoplasms

,

cholangiocarcinoma

,

pleural effusion

,

malignant pleural effusion

,

,

,

adenosquamous carcinoma

,

gastrointestinal stromal tumors

,

,

hemangiosarcoma

,

hyperthermic intraperitoneal chemotherapy

,

synovial sarcoma

,

urogenital neoplasms

,

thymus neoplasms

,

small cell carcinoma

,

dna repair-deficiency disorders

,

thyroid diseases

,

uterine neoplasms

,

myeloid leukemia acute

,

,

,

carcinoma in situ

,

,

germ cell and embryonal neoplasms

,

,

large cell carcinoma

,

,

papillomaviridae

,

neuroendocrine carcinoma

,

residual neoplasm

,

,

,

cognitive dysfunction

,

myeloproliferative disorders

,

multiple myeloma

,

alopecia areata

,

,

lacrimal apparatus diseases

,

adrenocortical carcinoma

,

,

heavy ion radiotherapy

,

merkel cell carcinoma

,

microsatellite instability

,

breast carcinoma in situ

,

lobular carcinoma

,

testicular neoplasms

,

branchio-oto-renal syndrome

,

,

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

,

,

somatoform disorders

,

disseminated intravascular coagulation

,

tonsillar neoplasms

,

glandular and epithelial neoplasms

,

,

cardiovascular diseases

,

,

intraductal carcinoma noninfiltrating

,

anaplastic thyroid carcinoma

,

antineoplastic combined chemotherapy protocols

,

,

urologic diseases

,

urinary bladder diseases

,

,

papillomavirus infections

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

lymphatic metastasis

,

,

bone marrow diseases

,

epstein-barr virus infections

,

,

hormone-dependent neoplasms

,

ampulla of vater cancer

,

gastrointestinal diseases

,

digestive system diseases

,

mycobacterium infections

,

mediastinal neoplasms

,

palliative care

,

mullerian mixed tumor

,

pancoast syndrome

,

penile neoplasms

,

thromboembolism

,

intestinal neoplasms

,

myelodysplastic syndromes

,

precancerous conditions

,

plasma cell neoplasms

,

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

adenoid cystic carcinoma

,

intestinal obstruction

,

alphapapillomavirus

,

carcinoid tumor

,

,

pancreatic ductal carcinoma

,

hodgkin disease

,

maxillary sinus neoplasms

,

adolescent development

,

,

cancer vaccines

,

radiation effects

,

perioperative period

,

,

ovarian neoplasms

,

nasopharyngeal carcinoma

,

,

nasopharyngeal neoplasms

,

,

ovarian epithelial carcinoma

,

pancreatic neoplasms

,

urinary bladder neoplasms

,

esophageal squamous cell carcinoma

,

urologic neoplasms

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

hypersensitivity

,

uterine cervical neoplasms

,

peritoneal neoplasms

,

small cell lung carcinoma

,

laryngeal neoplasms

,

endometrial neoplasms

,

oropharyngeal neoplasms

,

,

renal cell carcinoma

,

hypopharyngeal neoplasms

,

inflammatory breast neoplasms

,

salivary gland neoplasms

,

mouth neoplasms

,

,

,

chemotherapy-induced febrile neutropenia

,

disease progression

,

neoadjuvant therapy

,

non-muscle invasive bladder neoplasms

,

invasive hydatidiform mole

,

laryngeal diseases

,

drug-related side effects and adverse reactions

,

gastrointestinal neoplasms

,

,

,

unknown primary neoplasms

,

ureteral neoplasms

,

malignant fibrous histiocytoma

,

,

tongue neoplasms

,

digestive system neoplasms

,

urethral neoplasms

,

brain stem neoplasms

,

paranasal sinus neoplasms

,

circulating neoplastic cells

,

endometrioid carcinoma

,

breast diseases

,

bronchiolo-alveolar adenocarcinoma

,

hereditary breast and ovarian cancer syndrome

,

disease-free survival

,

verrucous carcinoma

,

brain neoplasms

,

cystadenocarcinoma

,

chemoradiotherapy

,

rhabdomyosarcoma

,

,

mucinous cystadenocarcinoma

,

mucinous adenocarcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

neoplasms by site

,

local neoplasm recurrence

,

ductal carcinoma breast

,

bronchogenic carcinoma

,

ductal carcinoma

,

neurotoxicity syndromes

,

healthy volunteers/patients

,

,

progression-free survival

,

postoperative complications

,

,

acinar cell carcinoma

,

,

pelvic neoplasms

,

induction chemotherapy

,

respiratory tract diseases

,

,

respiratory tract neoplasms

,

thoracic neoplasms

,

bronchial neoplasms

,

genetic predisposition to disease

,

disease susceptibility

,

,

pharyngeal neoplasms

,

wasting syndrome

,

,

,

therapeutic equivalency

,

adenomyoepithelioma

,

,

directly observed therapy

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

,

,

stomach neoplasms

,

,

squamous cell carcinoma

,

esophageal neoplasms

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

castration-resistant prostatic neoplasms

,

triple negative breast neoplasms

,

neoplasm metastasis

,

squamous cell neoplasms

,

,

adenocarcinoma of lung

,

male breast neoplasms

,

peripheral nervous system diseases

,

febrile neutropenia

,

,

second primary neoplasms

,

wounds and injuries

,

chemical and drug induced liver injury

,

meningeal carcinomatosis

,

,

,

,

,

,

breast cancer lymphedema

,

taste disorders

,

,

,

,

,

prospective studies

,

pharmacogenomic testing

,

,

chemotherapy-related cognitive impairment

,

,

,

,

postoperative pain

,

,

,

,

pathologic complete response

,

hand-foot syndrome

,

intravesical administration

,

mycobacterium bovis

,

medical sociology

,

castration-resistant prostatic neoplasms

,

prostatic neoplasms

,

breast neoplasms

,

ovarian neoplasms

,

renal cell carcinoma

,

non-hodgkin lymphoma

,

,

non-small-cell lung carcinoma

,

,

transitional cell carcinoma

myeloid leukemia acute

,

,

myeloid leukemia

,

bone marrow transplantation

,

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