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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

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Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

breast neoplasms

,

,

non-hodgkin lymphoma

,

,

,

prostatic neoplasms

,

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

precursor cell lymphoblastic leukemia-lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

hematologic neoplasms

,

,

diffuse intrinsic pontine glioma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

myelomonocytic leukemia juvenile

,

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

myelomonocytic leukemia acute

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

bronchiolitis obliterans syndrome

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

,

phenylketonurias

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

myelodysplastic syndromes

,

,

hodgkin disease

,

myeloid leukemia

,

myeloid leukemia acute

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

,

,

non-hodgkin lymphoma

,

multiple myeloma

,

hodgkin disease

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

lymphoid leukemia

,

,

b-cell chronic lymphocytic leukemia

,

reactive arthritis

,

,

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

bipolar disorder

healthy volunteers/patients

,

second primary neoplasms

,

communicable diseases

,

,

synovial sarcoma

,

myxoid liposarcoma

,

b-cell leukemia

,

chronic hepatitis d

,

,

alveolar soft part sarcoma

,

,

thymus neoplasms

,

,

large cell carcinoma

,

,

liver transplantation

,

urethral neoplasms

,

ureteral neoplasms

,

pelvic neoplasms

,

meningeal neoplasms

,

meningeal carcinomatosis

,

t-cell lymphoma cutaneous

,

urogenital neoplasms

,

,

,

mycosis fungoides

,

vesicular stomatitis

,

local neoplasm recurrence

,

,

neoadjuvant therapy

,

castration-resistant prostatic neoplasms

,

pancreatic ductal carcinoma

,

,

b-cell lymphoma

,

,

adenocarcinoma of lung

,

thyroid neoplasms

,

,

microsatellite instability

,

multiple myeloma

,

parkinson disease

,

gastrointestinal neoplasms

,

plasma cell neoplasms

,

cutaneous malignant melanoma

,

myeloid leukemia acute

,

endometrioid carcinoma

,

neuroendocrine tumors

,

,

digestive system neoplasms

,

colonic neoplasms

,

myeloid leukemia

,

drug-related side effects and adverse reactions

,

oropharyngeal neoplasms

,

,

residual neoplasm

,

clear cell adenocarcinoma

,

thyroid diseases

,

follicular lymphoma

,

,

non-hodgkin lymphoma

,

,

extranodal nk-t-cell lymphoma

,

myelodysplastic syndromes

,

adenomyoepithelioma

,

female genital neoplasms

,

basal cell carcinoma

,

basal cell neoplasms

,

hematologic neoplasms

,

salivary gland neoplasms

,

mouth neoplasms

,

malignant mesothelioma

,

precursor cell lymphoblastic leukemia-lymphoma

,

neuroendocrine carcinoma

,

,

mucinous adenocarcinoma

,

cystadenocarcinoma

,

serous cystadenocarcinoma

,

gastrointestinal stromal tumors

,

adenoid cystic carcinoma

,

adrenocortical carcinoma

,

vulvar neoplasms

,

large-cell lymphoma anaplastic

,

peritoneal neoplasms

,

malignant fibrous histiocytoma

,

,

,

acquired immunodeficiency syndrome

,

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

,

therapeutic chemoembolization

,

uterine neoplasms

,

bronchogenic carcinoma

,

small cell carcinoma

,

,

lymphoid leukemia

,

tertiary lymphoid structures

,

organ preservation

,

anaplastic thyroid carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

unknown primary neoplasms

,

pheochromocytoma

,

mucinous cystadenocarcinoma

,

germ cell and embryonal neoplasms

,

,

,

gallbladder neoplasms

,

hemangiosarcoma

,

bronchiolo-alveolar adenocarcinoma

,

islet cell carcinoma

,

choriocarcinoma

,

parathyroid neoplasms

,

,

sex cord-gonadal stromal tumors

,

neurofibrosarcoma

,

mesothelial neoplasms

,

papillary adenocarcinoma

,

acinar cell carcinoma

,

perivascular epithelioid cell neoplasms

,

trophoblastic neoplasms

,

paranasal sinus neoplasms

,

,

nerve sheath neoplasms

,

giant cell carcinoma

,

,

,

pseudomyxoma peritonei

,

extramammary paget disease

,

spinal neoplasms

,

tracheal neoplasms

,

prostatic diseases

,

,

bronchopulmonary dysplasia

,

tobacco smoking

,

adrenal cortex neoplasms

,

progression-free survival

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

inflammatory breast neoplasms

,

b-cell lymphoma marginal zone

,

bile duct neoplasms

,

carcinoid tumor

,

respiratory tract diseases

,

respiratory tract neoplasms

,

bronchial neoplasms

,

induction chemotherapy

,

nasopharyngeal diseases

,

,

papillomaviridae

,

penile neoplasms

,

,

,

esophageal diseases

,

,

,

,

adenoviridae infections

,

,

rheumatoid arthritis

,

,

alopecia areata

,

,

fertility preservation

,

intraoperative complications

,

,

maintenance chemotherapy

,

,

,

,

colorectal neoplasms

,

liver neoplasms

,

squamous cell carcinoma

,

squamous cell carcinoma of head and neck

,

,

renal cell carcinoma

,

esophageal neoplasms

,

triple negative breast neoplasms

,

head and neck neoplasms

,

esophageal squamous cell carcinoma

,

pancreatic neoplasms

,

small cell lung carcinoma

,

,

uterine cervical neoplasms

,

ovarian neoplasms

,

neoplasm metastasis

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

urologic neoplasms

,

rectal neoplasms

,

ovarian epithelial carcinoma

,

prostatic neoplasms

,

cholangiocarcinoma

,

squamous cell neoplasms

,

urinary bladder neoplasms

,

large b-cell lymphoma diffuse

,

,

endometrial neoplasms

,

transitional cell carcinoma

,

,

merkel cell carcinoma

,

brain neoplasms

,

,

kidney neoplasms

,

,

fallopian tube neoplasms

,

chemoradiotherapy

,

,

mullerian mixed tumor

,

uveal neoplasms

,

hypersensitivity

,

molecular targeted therapy

,

hypopharyngeal neoplasms

,

laryngeal neoplasms

,

transplantation

,

,

,

hemophagocytic lymphohistiocytosis

,

human herpesvirus 4

,

non-small-cell lung carcinoma

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

,

breast neoplasms

,

,

hodgkin disease

,

biliary tract neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

,

,

chronic hepatitis b

,

chronic hepatitis

,

,

epstein-barr virus infections

,

,

herpesviridae infections

,

,

neurodegenerative diseases

,

human influenza

,

,

alzheimer disease

,

positron-emission tomography

,

tumor microenvironment

,

,

,

,

interstitial lung diseases

,

disease progression

,

cardiovascular abnormalities

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

,

,

,

shy-drager syndrome

,

multiple system atrophy

,

,

progressive supranuclear palsy

,

movement disorders

,

magnetic resonance imaging

,

x-ray computed tomography

,

,

speech intelligibility

,

immunoblastic lymphadenopathy

,

immune system diseases

,

autoimmune diseases

,

lewy body disease

,

,

cognitive dysfunction

,

nerve degeneration

,

inborn genetic diseases

,

nervous system diseases

,

nervous system heredodegenerative disorders

,

synucleinopathies

,

irritable bowel syndrome

,

catheter ablation

,

,

,

sleep wake disorders

,

,

circadian rhythm sleep disorders

,

,

,

pancreatic neoplasms

,

inflammatory bowel diseases

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

renal insufficiency

,

brain neoplasms

,

glandular and epithelial neoplasms

,

,

delayed graft function

,

hypersensitivity

,

venous thromboembolism

,

thromboembolism

,

pharmacokinetics

,

,

central nervous system diseases

,

,

,

endometrial neoplasms

,

,

mullerian mixed tumor

,

,

,

breast neoplasms

,

rheumatoid arthritis

,

,

b-cell chronic lymphocytic leukemia

,

neoplasm metastasis

,

,

non-hodgkin lymphoma

,

,

colorectal neoplasms

,

small cell lung carcinoma

,

ulcerative colitis

,

,

,

,

triple negative breast neoplasms

,

autoimmune diseases

,

,

kidney neoplasms

,

female genital neoplasms

,

biliary tract neoplasms

,

neuroendocrine tumors

,

,

kidney transplantation

,

,

diffuse intrinsic pontine glioma

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

,

lipoid nephrosis

,

discoid lupus erythematosus

,

lupus nephritis

,

,

,

diabetic nephropathies

,

kidney diseases

,

atopic dermatitis

,

,

,

alopecia areata

,

,

hematologic neoplasms

,

gastrointestinal neoplasms

,

esophageal neoplasms

,

pancreatic ductal carcinoma

,

hidradenitis suppurativa

,

,

polycythemia vera

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

,

gastrointestinal stromal tumors

,

,

alveolar soft part sarcoma

,

solitary fibrous tumors

,

,

rhabdomyosarcoma

,

primitive neuroectodermal tumors peripheral

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

giant cell tumor of bone

,

giant cell tumors

,

hemangiopericytoma

,

adenocarcinoma of lung

,

merkel cell carcinoma

,

castration-resistant prostatic neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

non-small-cell lung carcinoma

,

,

renal cell carcinoma

,

lymphoid leukemia

,

multiple myeloma

,

philadelphia chromosome

,

,

prostatic neoplasms

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

psoriatic arthritis

,

hepatocellular carcinoma

,

liver neoplasms

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

,

myeloid leukemia accelerated phase

,

sjogren's syndrome

,

squamous cell carcinoma

,

rheumatic diseases

,

juvenile arthritis

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

healthy volunteers/patients

,

,

systemic lupus erythematosus

,

myeloid leukemia chronic-phase

,

cutaneous lupus erythematosus

,

coronary artery disease

,

pleural effusion

,

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

alzheimer disease

,

progressive supranuclear palsy

,

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

healthy volunteers/patients

,

neoplasm metastasis

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

philadelphia chromosome

,

castration-resistant prostatic neoplasms

,

,

stomach neoplasms

,

,

hepatic insufficiency

,

triple negative breast neoplasms

,

hereditary breast and ovarian cancer syndrome

,

retinal diseases

,

diabetic retinopathy

,

,

,

liver neoplasms

,

hepatocellular carcinoma

,

,

colorectal neoplasms

,

,

myeloid leukemia

,

adenoid cystic carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

,

neoadjuvant therapy

,

myeloid leukemia acute

,

gastrointestinal stromal tumors

,

endometrial neoplasms

,

pheochromocytoma

,

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

,

prostatic neoplasms

,

,

breast neoplasms

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

disease progression

,

biliary tract neoplasms

,

,

non-hodgkin lymphoma

,

multiple myeloma

,

salivary gland neoplasms

,

alveolar soft part sarcoma

,

solitary fibrous tumors

,

hemangiopericytoma

,

fibrous tissue neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

uveal neoplasms

,

squamous cell carcinoma

,

carcinoid tumor

,

lymphatic metastasis

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

nasopharyngeal carcinoma

,

malignant mesothelioma

,

,

hemangiosarcoma

,

,

myelodysplastic syndromes

,

,

superior vena cava syndrome

,

ductal carcinoma

,

medulloblastoma

,

,

molecular targeted therapy

,

,

,

non-small-cell lung carcinoma

,

macular degeneration

,

wet macular degeneration

,

pancreatic neoplasms

,

ovarian neoplasms

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

,

renal cell carcinoma

,

kidney neoplasms

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

drug-related side effects and adverse reactions

,

uterine cervical neoplasms

,

,

mantle-cell lymphoma

,

hand-foot syndrome

,

non-small-cell lung carcinoma

,

,

female genital neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

hodgkin disease

,

blastic plasmacytoid dendritic cell neoplasm

,

non-small-cell lung carcinoma

,

,

gata2 deficiency

,

pancreatic neoplasms

,

,

,

,

,

disease progression

,

male breast neoplasms

,

kidney diseases

,

renal insufficiency

,

retinal diseases

,

systemic lupus erythematosus

,

hemophagocytic lymphohistiocytosis

,

adenoid cystic carcinoma

,

triple negative breast neoplasms

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

hematologic neoplasms

,

follicular lymphoma

,

myeloproliferative disorders

,

bcr-abl positive chronic myelogenous leukemia

,

b-cell lymphoma marginal zone

,

myelomonocytic leukemia acute

,

residual neoplasm

,

philadelphia chromosome

,

hematopoietic stem cell transplantation

,

,

breast neoplasms

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

myelodysplastic-myeloproliferative diseases

,

neoplasm metastasis

,

,

burkitt lymphoma

,

immunoglobulin light-chain amyloidosis

,

primary myelofibrosis

,

,

healthy volunteers/patients

,

myeloid leukemia chronic-phase

,

small cell lung carcinoma

,

prolymphocytic leukemia

,

t-cell lymphoma cutaneous

,

prolymphocytic leukemia t-cell

,

refractory anemia with excess of blasts

,

monocytic leukemia acute

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

leukemia myeloid chronic atypical bcr-abl negative

,

myeloid leukemia accelerated phase

,

,

eyelid neoplasms

,

,

colorectal neoplasms

,

myeloid sarcoma

,

salvage therapy

,

erythroblastic leukemia acute

,

hypersensitivity

,

hematologic diseases

,

essential thrombocythemia

,

polycythemia vera

,

neutrophilic leukemia chronic

,

hypereosinophilic syndrome

,

,

large-cell lymphoma anaplastic

,

t-cell leukemia

,

respiratory aspiration

,

,

,

,

pneumococcal pneumonia

,

hairy cell leukemia

,

,

,

myelodysplastic syndromes

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

,

,

,

mantle-cell lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

biphenotypic leukemia acute

,

promyelocytic leukemia acute

,

bone marrow transplantation

,

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

lymphoid leukemia

,

b-cell chronic lymphocytic leukemia

,

,

,

plasma cell leukemia

,

congenital abnormalities

,

eye abnormalities

,

chromosome aberrations

,

chromosome disorders

,

cardiac arrhythmias

,

sudden death cardiac

,

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