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Trade Name	Drug Name	Approved	Patent Expires	Indication
Copiktra	Duvelisib	2018-09-24	2029-2032	B-cell chronic lymphocytic leukemia , Follicular lymphoma
Farydak	Panobinostat	2015-02-23	2028	Multiple myeloma

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

non-small-cell lung carcinoma

,

liver neoplasms

,

head and neck neoplasms

,

triple negative breast neoplasms

,

castration-resistant prostatic neoplasms

,

myeloproliferative disorders

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia accelerated phase

,

malignant mesothelioma

,

,

hepatocellular carcinoma

,

nasopharyngeal carcinoma

,

,

,

,

,

sickle cell anemia

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

,

medulloblastoma

,

,

,

myeloid leukemia

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

prostatic neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

hematologic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

large b-cell lymphoma diffuse

,

diffuse intrinsic pontine glioma

,

b-cell lymphoma

,

t-cell lymphoma cutaneous

,

b-cell chronic lymphocytic leukemia

,

t-cell leukemia

,

mantle-cell lymphoma

,

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

myeloid leukemia chronic-phase

,

neoplasm metastasis

,

,

lymphoid leukemia

,

extranodal nk-t-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

kidney neoplasms

,

waldenstrom macroglobulinemia

,

adult t-cell leukemia-lymphoma

,

,

brain neoplasms

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

sezary syndrome

,

lymphoproliferative disorders

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mycosis fungoides

,

burkitt lymphoma

,

,

essential thrombocythemia

,

,

,

colorectal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

plasma cell leukemia

,

biphenotypic leukemia acute

,

,

stomach neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

neuroendocrine tumors

,

thrombocytopenia

,

interdigitating dendritic cell sarcoma

,

,

phenylketonurias

,

,

multiple myeloma

,

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

hodgkin disease

,

,

myeloid leukemia acute

,

primary myelofibrosis

,

graft vs host disease

,

polycythemia vera

,

bronchiolitis obliterans syndrome

,

non-hodgkin lymphoma

,

,

multiple myeloma

,

hodgkin disease

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

large-cell lymphoma anaplastic

,

lymphoid leukemia

,

,

b-cell chronic lymphocytic leukemia

,

reactive arthritis

,

,

,

,

head and neck neoplasms

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

anxiety disorders

,

healthy volunteers/patients

,

huntington disease

,

non-alcoholic fatty liver disease

,

,

,

,

,

breast neoplasms

,

,

chronic hepatitis b

,

chronic hepatitis

,

parkinson disease

,

eosinophilic esophagitis

,

,

biliary liver cirrhosis

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

diffuse scleroderma

,

,

,

,

short bowel syndrome

,

myocardial infarction

,

drug resistance

,

heat stress disorders

,

,

combat disorders

,

traumatic stress disorders

,

gastrointestinal diseases

,

,

intestinal diseases

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

depressive disorder

,

,

,

major depressive disorder

,

,

,

,

kidney diseases

,

,

cardiovascular diseases

,

chronic renal insufficiency

,

chronic hepatitis c

,

papillomavirus infections

,

,

,

pulmonary embolism

,

,

thromboembolism

,

,

venous thrombosis

,

,

papillomavirus vaccines

,

,

meningococcal infections

,

,

glucose metabolism disorders

,

metabolic diseases

,

vascular diseases

,

,

metabolic syndrome

,

endocrine system diseases

,

hypertriglyceridemia

,

rheumatoid arthritis

,

atrial fibrillation

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

systemic scleroderma

,

juvenile arthritis

,

behcet syndrome

,

dermatomyositis

,

ankylosing spondylitis

,

sjogren's syndrome

,

systemic lupus erythematosus

,

,

spondylarthritis

,

systemic vasculitis

,

diabetic neuropathies

,

hypercholesterolemia

,

,

facial nerve diseases

,

,

wasting syndrome

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

ovarian neoplasms

,

kidney neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic diseases

,

myelomonocytic leukemia chronic

,

myeloid leukemia

,

myelomonocytic leukemia juvenile

,

,

bone marrow diseases

,

,

gastrointestinal stromal tumors

,

,

multiple myeloma

,

plasma cell neoplasms

,

alveolar soft part sarcoma

,

,

,

microsatellite instability

,

thymus neoplasms

,

cutaneous malignant melanoma

,

,

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

triple negative breast neoplasms

,

hepatocellular carcinoma

,

renal cell carcinoma

,

liver neoplasms

,

breast neoplasms

,

,

,

ovarian epithelial carcinoma

,

,

squamous cell carcinoma of head and neck

,

,

small cell lung carcinoma

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

pancreatic ductal carcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

pancreatic neoplasms

,

esophageal squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

neuroendocrine tumors

,

malignant mesothelioma

,

urologic neoplasms

,

thyroid neoplasms

,

esophageal neoplasms

,

uterine cervical neoplasms

,

cholangiocarcinoma

,

unknown primary neoplasms

,

adenocarcinoma of lung

,

clear cell adenocarcinoma

,

,

uveal neoplasms

,

adenomyoepithelioma

,

,

hematologic neoplasms

,

anaplastic thyroid carcinoma

,

neuroendocrine carcinoma

,

,

brain neoplasms

,

,

,

diffuse intrinsic pontine glioma

ovarian neoplasms

,

,

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

liver neoplasms

,

nervous system neoplasms

,

testicular neoplasms

,

,

small cell lung carcinoma

healthy volunteers/patients

,

gastrointestinal neoplasms

,

follicular lymphoma

,

pancreatic neoplasms

,

hepatocellular carcinoma

,

digestive system neoplasms

,

neoplasm metastasis

,

respiratory tract diseases

,

pleural effusion

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

neoplasms by site

,

malignant pleural effusion

,

pleural diseases

,

pleural neoplasms

,

myeloid leukemia acute

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

multiple myeloma

,

chronic hepatitis c

,

,

,

adenocarcinoma of lung

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

colorectal neoplasms

,

,

non-hodgkin lymphoma

,

,

breast neoplasms

,

,

,

pulmonary embolism

,

,

papulosquamous skin diseases

,

essential hypertension

,

restless legs syndrome

,

,

rheumatoid arthritis

,

respiratory distress syndrome

,

vascular access devices

,

catheter obstruction

,

,

ischemic stroke

,

,

type 1 diabetes mellitus

,

,

polycystic kidney diseases

,

,

myocardial infarction

,

,

,

kidney diseases

,

diabetic neuropathies

,

diabetic nephropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

liver cirrhosis

,

parkinson disease

,

peripheral arterial disease

,

intermittent claudication

,

peripheral vascular diseases

,

,

disease progression

,

hypersensitivity

,

extrinsic allergic alveolitis

Globulin, immune

healthy volunteers/patients

,

renal insufficiency

,

,

bites and stings

,

small cell lung carcinoma

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

bone marrow failure disorders

,

,

electrocardiography

,

transplantation

,

,

hepatic insufficiency

,

male breast neoplasms

,

dermatomyositis

,

inclusion body myositis

,

dna repair-deficiency disorders

,

hereditary congenital and neonatal diseases and abnormalities

,

,

hypoplastic anemia congenital

,

hemic and lymphatic diseases

,

adenosquamous carcinoma

,

,

head and neck neoplasms

,

kidney neoplasms

,

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

squamous cell neoplasms

,

renal cell carcinoma

,

,

,

,

pancreatic neoplasms

,

squamous cell carcinoma

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

carcinoid tumor

,

type 1 diabetes mellitus

,

aplastic anemia

,

smoldering multiple myeloma

,

gastrointestinal neoplasms

,

urinary bladder neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

philadelphia chromosome

,

hematopoietic stem cell transplantation

,

thyroid neoplasms

,

hodgkin disease

,

endocrine gland neoplasms

,

parathyroid neoplasms

,

,

giant cell tumors

,

second primary neoplasms

,

hemangiosarcoma

,

fracture healing

,

chronic urticaria

,

,

post-traumatic headache

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

mucocutaneous lymph node syndrome

,

cutaneous malignant melanoma

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

graft vs host disease

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

waldenstrom macroglobulinemia

,

urologic neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

serotonin syndrome

,

malignant pleural effusion

,

circulating neoplastic cells

,

biliary tract neoplasms

,

gallbladder neoplasms

,

myelomonocytic leukemia juvenile

,

pleomorphic adenoma

,

replacement arthroplasty hip

,

,

,

aneurysmal bone cysts

,

giant cell granuloma

,

,

chondroblastoma

,

chronic kidney failure

,

,

brain neoplasms

,

kidney transplantation

,

graft rejection

,

psychology rejection

,

kidney diseases

,

iga glomerulonephritis

,

,

invasive hydatidiform mole

,

,

breast neoplasms

,

neoplasm metastasis

,

non-small-cell lung carcinoma

,

rectal neoplasms

,

colonic neoplasms

,

multiple myeloma

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

castration-resistant prostatic neoplasms

,

,

stomach neoplasms

,

,

,

,

,

plasma cell neoplasms

,

lymphoid leukemia

,

inflammatory breast neoplasms

,

follicular lymphoma

,

mucinous adenocarcinoma

,

,

hematologic neoplasms

,

,

,

osteogenesis imperfecta

,

ductal carcinoma breast

,

spinal cord compression

,

,

,

,

febrile neutropenia

,

musculoskeletal diseases

,

hematologic diseases

,

blood protein disorders

,

,

bone marrow diseases

,

paraproteinemias

,

neoplastic processes

,

multiple endocrine neoplasia type 1

,

,

personal satisfaction

,

,

ankylosing spondylitis

,

homozygous familial hypercholesterolemia

,

human influenza

,

atopic dermatitis

,

,

,

esophageal squamous cell carcinoma

,

phenylketonurias

,

feeding and eating disorders

,

anorexia nervosa

,

,

immunoglobulin g4-related disease

,

,

colorectal neoplasms

,

,

,

rheumatoid arthritis

,

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

,

hyperlipidemias

,

,

psoriatic arthritis

,

hypercholesterolemia

,

giant cell tumor of bone

,

juvenile arthritis

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

graves ophthalmopathy

,

,

,

hyperlipoproteinemias

,

diabetes mellitus

,

hyperlipoproteinemia type ii

,

primary hyperparathyroidism

,

,

,

neuromyelitis optica

,

metabolic syndrome

,

insulin resistance

,

autoimmune diseases

,

,

,

,

microvascular angina

,

t-cell lymphoma peripheral

,

coronary artery disease

,

myocardial ischemia

,

atherosclerosis

,

hidradenitis suppurativa

,

thyroid diseases

castration-resistant prostatic neoplasms

,

squamous cell carcinoma of head and neck

,

prostatic neoplasms

,

,

,

,

,

squamous cell carcinoma

,

colorectal neoplasms

,

pancreatic neoplasms

,

gastrointestinal neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

malignant fibrous histiocytoma

,

dermatofibrosarcoma

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